One of the most important tasks in clustering analysis is the analysis of genomic profiles to attribute individuals to specific ethnic populations, or the analysis of nucleotide haplotypes for diseases susceptibility. Human ancestry from Asia, Europe, Africa, and the Americas can be separated based on their genomic data. Research has shown that the Y chromosome lineage can be geographically localized, forming the evidence for clustering the human alleles of the human genotypes. According to National Cancer Institute (https://www.cancer.gov/publications/dictionaries/genetics-dictionary/def/genetic-variant):
"Genetic variants are an alteration in the most common DNA nucleotide sequence. The term variant can be used to describe an alteration that may be benign, pathogenic, or of unknown significance. The term variant is increasingly being...