The same as the previous two cases, static analysis is not a big problem as there are multiple tools that support PPC architecture, for example, radare2, IDA, Binary Ninja, ODA or Hopper.
In terms of dynamic analysis, the combination of QEMU and either IDA or GDB should do the trick:
Figure 13: Debugging Mirai sample built for PowerPC in IDA on Windows via a remote QEMU GDB server running on the x86 VM
As we can see, less prevalent architectures may require a more sophisticated setup in order to perform comfortable debugging.