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R Bioinformatics Cookbook

You're reading from   R Bioinformatics Cookbook Utilize R packages for bioinformatics, genomics, data science, and machine learning

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Product type Paperback
Published in Oct 2023
Publisher Packt
ISBN-13 9781837634279
Length 396 pages
Edition 2nd Edition
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Author (1):
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Dan MacLean Dan MacLean
Author Profile Icon Dan MacLean
Dan MacLean
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Table of Contents (16) Chapters Close

Preface 1. Chapter 1: Setting Up Your R Bioinformatics Working Environment 2. Chapter 2: Loading, Tidying, and Cleaning Data in the tidyverse FREE CHAPTER 3. Chapter 3: ggplot2 and Extensions for Publication Quality Plots 4. Chapter 4: Using Quarto to Make Data-Rich Reports, Presentations, and Websites 5. Chapter 5: Easily Performing Statistical Tests Using Linear Models 6. Chapter 6: Performing Quantitative RNA-seq 7. Chapter 7: Finding Genetic Variants with HTS Data 8. Chapter 8: Searching Gene and Protein Sequences for Domains and Motifs 9. Chapter 9: Phylogenetic Analysis and Visualization 10. Chapter 10: Analyzing Gene Annotations 11. Chapter 11: Machine Learning with mlr3 12. Chapter 12: Functional Programming with purrr and base R 13. Chapter 13: Turbo-Charging Development in R with ChatGPT 14. Index 15. Other Books You May Enjoy

Dimension reduction with PCA in mlr3 pipelines

Principal Component Analysis (PCA) is a dimensionality reduction technique commonly used in bioinformatics to analyze and interpret high-dimensional biological data, such as gene expression data, protein profiles, or genomic data.

The main goal of PCA is to find a lower-dimensional representation of the data while preserving the most important patterns and variability present in the original data. It achieves this by transforming the data into a new set of uncorrelated variables called principal components. These principal components are ordered in such a way that the first component captures the maximum amount of variance in the data, the second component captures the second maximum variance, and so on.

PCA is useful in bioinformatics for various applications, including visualization, as it reduces data to two or three dimensions for use in plots. PCA has an important role in feature selection in ML, as it can be used to select...

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