As the saying goes:
"Just because you're not paranoid doesn't mean they aren't after you."
–Joseph Heller.
–Joseph Heller.
In the web world, hackers are continually scanning your servers and sites regardless of who you are and what sort of site you have. In 99 percent of all instances, they don't care who you are or what your site is, but only see how easily they can manipulate it to do what they want.
Even if you're 100 percent sure that your website is secure, you can save a lot of CPU cycles and potential Denial of Service (DOS) attacks by blocking these agents.