Multiprocessing
Let's be honest, multithreading is challenging. Dealing with threads in a sane and safe manner required a tremendous amount of code when compared to the synchronous approach. We had to set up a thread pool and communication queues, gracefully handle exceptions from threads, and also worry about thread safety when trying to provide a rate limiting capability. Dozens of lines of code are needed just to execute one function from some external library in parallel! And we rely on the promise from the external package creator that their library is thread-safe. Sounds like a high price for a solution that is practically applicable only for doing I/O-bound tasks.
An alternative approach that allows you to achieve parallelism is multiprocessing. Separate Python processes that do not constrain each other with the GIL allow for better resource utilization. This is especially important for applications running on multicore processors that are performing really CPU-intensive...