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Bioinformatics with Python Cookbook

You're reading from   Bioinformatics with Python Cookbook Learn how to use modern Python bioinformatics libraries and applications to do cutting-edge research in computational biology

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Product type Paperback
Published in Nov 2018
Publisher Packt
ISBN-13 9781789344691
Length 360 pages
Edition 2nd Edition
Languages
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Author (1):
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Tiago Antao Tiago Antao
Author Profile Icon Tiago Antao
Tiago Antao
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Table of Contents (12) Chapters Close

Preface 1. Python and the Surrounding Software Ecology 2. Next-Generation Sequencing FREE CHAPTER 3. Working with Genomes 4. Population Genetics 5. Population Genetics Simulation 6. Phylogenetics 7. Using the Protein Data Bank 8. Bioinformatics Pipelines 9. Python for Big Genomics Datasets 10. Other Topics in Bioinformatics 11. Advanced NGS Processing

Performing Principal Components Analysis

PCA is a statistical procedure that's used to perform a reduction of the dimension of a number of variables to a smaller subset that is linearly uncorrelated. Its practical application in population genetics is assisting with the visualization of the relationships between the individuals that are being studied.

While most of the recipes in this chapter make use of Python as a glue language (Python calls external applications that actually do most of the work), with PCA, we have an option: we can either use an external application (for example, EIGENSOFT SmartPCA), or use scikit-learn and perform everything on Python. We will perform both.

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