Making Views go fast
The last setting, Caching, is actually very important for Drupal performance. I'm surprised to see this view has caching disabled. If you remember way back when you started on this learning journey, one of the advanced Views general settings is to disable caching on a global basis. The description for this option says that it will have a serious performance impact on your site, which is really true. Views is a SQL query builder that can generate complex and time-consuming database queries. You don't want to execute them any more than you have to, especially if your data doesn't change in real time, which is true for most websites.
Caching types
Assuming you want caching, you need to decide what kind. One option is Time based, which is the kind of caching most used by Drupal 7 and before. This option basically says "wait for some period of time", an option that appears if you select the option when rerunning the query if you have already run it before. After this period...