If you want to be able to install applications with dependencies on different versions of the .NET Framework, then you should consider using the ASP.NET Core 2.0 framework, since it provides 100% side-by-side deployment capabilities.
Side-by-side deployments of different .NET Core and ASP.NET Core versions allow for having multiple services and applications on the same server. Each of them can be using their own dedicated versions of the respective frameworks, thus eliminating risks and saving money when doing application upgrades and common IT operations.
