With the latest release of BizTalk Server 2016, Microsoft introduced Logic Apps adapters, which are used for communicating between BizTalk Server and Logic Apps workflows running on the cloud.
BizTalk's Logic Apps adapter uses an on-premises data gateway to form hybrid connectivity with inbound workflows running on the cloud:
Logic Apps connectivity has made it possible to use multiple connectors in the cloud in conjunction with BizTalk Server. For example, it is now possible to connect to cloud SaaS offerings such as Azure Cognitive Services, Dropbox, and Slack with BizTalk, without any custom coding or having to buy any third-party BizTalk Server adapters.