This chapter in a nutshell

There are lots you can do to protect your PrestaShop. But there is always a way that a determined attacker can find a flaw with your security. Do everything you can; in fact, I suggest you seek further reading on general web security. A good starting point is an excellent article I found via the PrestaShop forums. Here it is:

http://www.smashingmagazine.com/2010/01/14/web-security-primer-are-you-part-of-the-problem/

But remember you are never totally secure. Always have a very recent backup ready to use.