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R Bioinformatics Cookbook

You're reading from   R Bioinformatics Cookbook Utilize R packages for bioinformatics, genomics, data science, and machine learning

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Product type Paperback
Published in Oct 2023
Publisher Packt
ISBN-13 9781837634279
Length 396 pages
Edition 2nd Edition
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Author (1):
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Dan MacLean Dan MacLean
Author Profile Icon Dan MacLean
Dan MacLean
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Table of Contents (16) Chapters Close

Preface 1. Chapter 1: Setting Up Your R Bioinformatics Working Environment 2. Chapter 2: Loading, Tidying, and Cleaning Data in the tidyverse FREE CHAPTER 3. Chapter 3: ggplot2 and Extensions for Publication Quality Plots 4. Chapter 4: Using Quarto to Make Data-Rich Reports, Presentations, and Websites 5. Chapter 5: Easily Performing Statistical Tests Using Linear Models 6. Chapter 6: Performing Quantitative RNA-seq 7. Chapter 7: Finding Genetic Variants with HTS Data 8. Chapter 8: Searching Gene and Protein Sequences for Domains and Motifs 9. Chapter 9: Phylogenetic Analysis and Visualization 10. Chapter 10: Analyzing Gene Annotations 11. Chapter 11: Machine Learning with mlr3 12. Chapter 12: Functional Programming with purrr and base R 13. Chapter 13: Turbo-Charging Development in R with ChatGPT 14. Index 15. Other Books You May Enjoy

Making predictions using linear models

Linear models are commonly used in bioinformatics for prediction tasks due to their simplicity, interpretability, and ability to handle high-dimensional datasets. In bioinformatics, researchers often work with large datasets that have a large number of features (such as gene expression data or sequence data), making it challenging to analyze them with more complex models. Linear models offer a straightforward and computationally efficient way to analyze these datasets. Linear models can help researchers identify genes or genetic variants that are associated with a particular trait or disease. They can also be used in feature selection, which is an important step in bioinformatics data analysis. Feature selection aims to identify the most relevant features (genes, proteins, etc.) that are associated with the outcome of interest (disease, drug response, etc.). Linear models can be used to rank features based on their importance and select the most...

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