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Bioinformatics with Python Cookbook

You're reading from   Bioinformatics with Python Cookbook Learn how to use modern Python bioinformatics libraries and applications to do cutting-edge research in computational biology

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Product type Paperback
Published in Nov 2018
Publisher Packt
ISBN-13 9781789344691
Length 360 pages
Edition 2nd Edition
Languages
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Author (1):
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Tiago Antao Tiago Antao
Author Profile Icon Tiago Antao
Tiago Antao
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Toc

Table of Contents (12) Chapters Close

Preface 1. Python and the Surrounding Software Ecology 2. Next-Generation Sequencing FREE CHAPTER 3. Working with Genomes 4. Population Genetics 5. Population Genetics Simulation 6. Phylogenetics 7. Using the Protein Data Bank 8. Bioinformatics Pipelines 9. Python for Big Genomics Datasets 10. Other Topics in Bioinformatics 11. Advanced NGS Processing

Exploring the data with standard statistics


Now that we have a compass from the decision tree, let's explore the data in order to get more insights that might help us to better filter the data. You can find this content in Chapter11/Exploration.ipynb.

How to do it…

  1. We start, as usual, with the necessary imports:
import gzip
import pickle
import random

import numpy as np
import matplotlib.pyplot as plt
import pandas as pd
from pandas.plotting import scatter_matrix

%matplotlib inline

 

 

  1. Then we load the data. We will use pandas to navigate it:
fit = np.load(gzip.open('balanced_fit.npy.gz', 'rb'))
ordered_features = np.load(open('ordered_features', 'rb'))
num_features = len(ordered_features)
fit_df = pd.DataFrame(fit, columns=ordered_features + ['pos', 'error'])
num_samples = 80
del fit
  1. Let's ask pandas to show an histogram of all annotations:
fig,ax = plt.subplots(figsize=(16,9))
fit_df.hist(column=ordered_features, ax=ax)

The following histogram is generated:

Histogram of all annotations for a dataset...

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