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Bioinformatics with Python Cookbook

You're reading from   Bioinformatics with Python Cookbook Learn how to use modern Python bioinformatics libraries and applications to do cutting-edge research in computational biology

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Product type Paperback
Published in Nov 2018
Publisher Packt
ISBN-13 9781789344691
Length 360 pages
Edition 2nd Edition
Languages
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Author (1):
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Tiago Antao Tiago Antao
Author Profile Icon Tiago Antao
Tiago Antao
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Table of Contents (12) Chapters Close

Preface 1. Python and the Surrounding Software Ecology 2. Next-Generation Sequencing FREE CHAPTER 3. Working with Genomes 4. Population Genetics 5. Population Genetics Simulation 6. Phylogenetics 7. Using the Protein Data Bank 8. Bioinformatics Pipelines 9. Python for Big Genomics Datasets 10. Other Topics in Bioinformatics 11. Advanced NGS Processing

Introduction


Pipelines are fundamental in any data science environment. Data processing is never a single task. Many pipelines are implemented via ad hoc scripts. This can be done in a useful way, but in many cases, they fail many fundamental viewpoints: reproducibility, maintainability, and extensibility.

In bioinformatics, you can find three main types of pipeline systems:

  • Frameworks like Galaxy (https://usegalaxy.org), which are geared toward users, that is, they expose easy-to-use user interfaces, hiding most of the underlying machinery
  • Frameworks like Script of Scripts (SoS) (https://vatlab.github.io/sos-docs/), which are geared toward data analysis, with a focus on with programming knowledge
  • Finally generic workflow systems like Apache Airflow (https://airflow.incubator.apache.org/), which take a less data-centered approach to workflow management

In this chapter, we will discuss Galaxy, which is especially important for bioinformaticians who are supporting users that are less inclined to...

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